The Indian Journal of Chest Diseases and Allied Sciences

Register      Login

VOLUME 57 , ISSUE 2 ( April-June, 2015 ) > List of Articles


Eosinophilic Granulomatosis with Polyangitis Presenting as Cardiac Tamponade

Sushil Kathar, Zarir F. Udwadia

Keywords : EGPA, Pericardial tamponade

Citation Information : Kathar S, Udwadia ZF. Eosinophilic Granulomatosis with Polyangitis Presenting as Cardiac Tamponade. Indian J Chest Dis Allied Sci 2015; 57 (2):121-123.

DOI: 10.5005/ijcdas-57-2-121

License: CC BY-NC 4.0

Published Online: 17-11-2022

Copyright Statement:  Copyright © 2015; The Author(s).


Eosinophilic granulomatosis with polyangitis (EGPA; earlier called Churg-Strauss syndrome) is a small-vessel necrotising vasculitis typically characterised by asthma, lung infiltrates, extra-vascular necrotising granulomas and hyper-eosinophilia. Cardiac disease is a major contributor to disease-related deaths in EGPA. We describe the case of a 39-year-old woman with late onset asthma, allergic rhinosinusitis, and high extra-vascular and peripheral blood eosinophilia, presenting with peripheral neuropathy and pericardial effusion. Early therapy with intravenous corticosteroids led to resolution of the pericardial effusion and significant clinical improvement. The present case also highlights the importance of being vigilant about potentially fatal cardiac complications in patients with EGPA.

PDF Share
  1. Guillevin L, Pagnoux C, Mouthon L. Churg-Strauss syndrome. Semin Respir Crit Care Med 2004;25:535-45.
  2. Bourgarit A, Le Toumelin P, Pagnoux C, Cohen P, Mahr A, Le Guern V, et al. Deaths occurring during the first year after treatment onset for polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: a retrospective analysis of causes and factors predictive of mortality based on 595 patients. Medicine 2005;84:323-30.
  3. Neumann T, Manger B, Schmid M, Kroegel C, Hansch A, Kaiser WA, et al. Cardiac involvement in Churg-Strauss syndrome: impact of endomyocarditis. Medicine 2009;88:236-43.
  4. Agard C, Rendu E, Leguern V, Ponge T, Masseau A, Barrier JH, et al. Churg-Strauss syndrome revealed by granulomatous acute pericarditis: two case reports and a review of the literature. Semin Arthritis Rheum 2007;36:386-91.
  5. Dennert RM, Van Paassen P, Schalla S, Kuznetsova T, Apzand BS, Staessen JA, et al. Cardiac involvement in Churg-Strauss syndrome. Arthritis Rheum 2010;62:627-34.
  6. Baili L, Aydi Z, Soussi G, Ben Dhaou BB, Zidi A, Berraies A, et al. Cardiac tamponade and myocarditis in Churg-Strauss syndrome. Ann Cardiol Angeiol (Paris) 2014;63:271-5.
  7. Suganuma K, Hashimoto T, Sato H, Suzuki T, Sakurai S. Oculomotor nerve palsy following cardiac tamponade with Churg- Strauss syndrome: a case report. Case Rep Neurol 2011;3:274-7.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.