Citation Information :
Prasad R, Srivastava A, Verma S. Clinico-pathological Profile of Bronchogenic Carcinoma Among Females in North India. Indian J Chest Dis Allied Sci 2015; 57 (3):161-163.
Objective. The present study was undertaken to explore the clinico-pathological profile of bronchogenic carcinoma among females.
Methods. One hundred and twenty-four female patients with histopathologically proven bronchogenic carcinoma who were hospitalised in the Department of Pulmonary Medicine, King George's Medical University, Lucknow from July 1985 to February 2007 were retrospectively studied.
Results. Their mean age was 61 years; 12.9 % of these were less than 40 years of age. Of these, 79% of female patients of lung cancer were first regarded as pulmonary tuberculosis; 76% belonged to rural area. Use of biomass fuel and kerosene oil exposure was the predominant risk factors evident among the 116 non-smoker women. Adenocarcinoma was observed in 43.5%, followed by squamous cell carcinoma in 33.1% and the remaining 23.4% cases were small cell carcinoma. The majority (77.4%) of non-small cell lung cancer (NSCLC) patients had advanced stage disease (IIIb and IV) and 58 % of small cell lung cancer (SCLC) patients had limited disease and 42 % of SCLC patients had extensive disease at the time of diagnosis.
Conclusion. Adenocarcinoma was found to be the most common histopathological type of bronchogenic carcinoma among these females.
World Health Organization. Cancer in developed countries: assessing the trends. WHO Chron 1985;39:109–11.
Nanda Kumar A. Consolidated report of the population based cancer registries, incidence and distribution of cancer, 1990-1996. National Cancer Registry Programme. New Delhi: Indian Council of Medical Resesarch; 2001.
Behera D, Balamugesh T. Lung cancer in India. Indian J Chest Dis Allied Sci 2004;46:269–81.
Behera D, Balamugesh T. Indoor air pollution as a risk factor for lung cancer in women. J Assoc Physicians India 2005;53:190–2.
Gao YT. Risk factors for lung cancer among nonsmokers with emphasis on lifestyle factors. Lung Cancer 1996;14:S39–S45.
Du YX, Cha Q, Chen XW, Chen YZ, Huang LF, Feng ZZ, et al. An epidemiological study of risk factors for lung cancer in Guangzhou, China. Lung Cancer 1996;14:S9–S37.
Wu JM, Du Y-x. Overview and highlights of the panel discussion. Lung Cancer 1996;14:S3–S8.
Smith KR. National burden of disease in India from indoor air pollution. (Inaugural article). Proc Natl Acad Sci USA 2000;97:13286–93.
Bal S. Screening for lung cancer. Hospital Today 2001;6:609–11.
Majumdar SK Das, Nanda S, Goirola M. Brachytherapy in lung cancer. Hospital Today 2001;6:609–11.
National Cancer Registry. Indian Council of Medical Research, Annual Report. New Delhi: Indian Council of Medical Research; 1986.
Notani P, Sanghavi LD. A retrospective study of lung cancer in Bombay. Br J Cancer 1974;29:47782.
Gupta RC, Purohit SD, Sharma MP, Bhardwaj S. Primary bronchogenic carcinoma: clinical profile of 279 cases from mid-west Rajasthan. Indian J Chest Dis Allied Sci 1998;40:109–16.
Medina FM, Barrera RR, Morales JF, Echegoyen RC, Chavarria JG, Rebora FT. Primary lung cancer in Mexico city: a report of 1019 cases. Lung Cancer 1996;14:185–93.
Bruce N, Perez-Padilla R, Albalak R. Indoor air pollution in developing countries: a major environmental and public health challenge. Bull World Health Organ 2000;78:1078–92.
Mountain CF. Revisions in the International System for staging Lung Cancer. Chest 1997;111:1710–7.
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74–108.
National Cancer Registry Programme. An epidemiological study. Indian Council of Medical Research, Biennial Report, 1988-1989. New Delhi: Indian Council of Medical Research.p.3–42.
Koo LC, Lee N, Ho J. Do cooking fuels pose a risk for lung cancer? a case-control study of women in Hong Kong. Ecol Dis 1983;2:255–65.
Khan NA, Afroz F, Lone MM, Teli MA, Muzaffar M, Jan N. Profile of lung cancer in Kashmir, India: a five-year study. Indian J Chest Dis Allied Sci 2006;48:187–90.
