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VOLUME 58 , ISSUE 2 ( April-June, 2016 ) > List of Articles

Original Article

Comparison of Effect of Levocetirizine or Montelukast Alone and in Combination on Symptoms of Allergic Rhinitis

Swayamsidha Andhale, Harish Chander Goel, Saispoorthi Nayak

Keywords : Allergic rhinitis, Montelukast, Levocetirizine

Citation Information : Andhale S, Goel HC, Nayak S. Comparison of Effect of Levocetirizine or Montelukast Alone and in Combination on Symptoms of Allergic Rhinitis. Indian J Chest Dis Allied Sci 2016; 58 (2):103-105.

DOI: 10.5005/ijcdas-58-2-103

License: CC BY-NC 4.0

Published Online: 17-11-2022

Copyright Statement:  Copyright © 2016; The Author(s).


Abstract

Objective: To determine the effect of levocetirizine, montelukast and the combination of both the drugs on symptoms of allergic rhinitis. Methods: Seventy-five patients with allergic rhinitis were randomly studied prospectively for a period of two weeks divided into three groups receiving either levocetrizine or montelukast or combination of both. The outcomes were measured by a visual analogue score for nasal and eye symptom during day-time and night-time. Results: All the three regimens were equally effective in improving the day-time symptoms, like sneezing and rhinorrhea. There was also no difference in the control of night-time and eye symptoms among the regimens. Conclusions: Montelukast, levocetirizine and their combination is equally effective in controlling symptoms, of allergic rhinitis. Thus, use of montelukast alone would be cost-effective and do avoid adverse effects of levocetirizine in combination therapy.

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