Citation Information :
Jasani N, Awad NT, Raut C. Effect of Coronary Artery Bypass Grafting Surgery on Pulmonary Function Tests and Arterial Blood Gases. Indian J Chest Dis Allied Sci 2016; 58 (3):161-164.
Background and Objective: Pulmonary dysfunction after open heart surgery is an important cause of post-operative morbidity. To evaluate effect of coronary artery bypass grafting (CABG) surgery on pulmonary functions and arterial blood gases (ABGs).
Methods: A prospective study was conducted at a pulmonary unit of a tertiary care public hospital. Of the 50 patients enrolled, 42 patients completed the study. Spirometry was performed one week pre-operatively and within four to five weeks post-operatively. Arterial blood gas samples were also collected just before spirometry. The pre- and post-operative data were compared.
Results: There was significant reduction in forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) by 13.8% and 13.1%, respectively within five weeks of surgery. After surgery mean maximum voluntary ventilation (MVV) showed a significant decrease of 7.6%. Post-operatively, the mean pH decreased significantly by 0.1% and the mean partial pressure of oxygen (PaO2) and oxygen saturation SpO2 showed significant decrease of 10.1% and 2.4%, respectively.
Conclusion: Coronary artery bypass grafting has an adverse impact on lung functions and ABGs.
Conti VR. Pulmonary injury after cardiopulmonary bypass. Chest 2001;119:2–4.
Vargas FS, Terra-Filho M, Hueb W, Teixeira RL, Cukier A, Light RW. Pulmonary function after coronary artery bypass surgery. Respir Med 1997;91:629–33.
Guizilini S, Gomes WJ, Faresin SM, Carvalho ACC, Jaramillo JI, Alves FA, et al. Efeitos do local de inserção do dreno pleural nafunçãopulmonar no pós-operatório de cirurgiaderevascularização do miocárdio. Rev Bras Cir Cardiovasc 2004;19:47–54.
Taggart DP, el-Fiky M, Carter R, Bowman A, Wheatley DJ. Respiratory dysfunction after uncomplicated cardiopulmonary bypass. Ann Thorac Surg 1993;56:1123–8.
Wynne R, Botti M. Postoperative pulmonary dysfunction in adults after cardiac surgery with cardiopulmonary bypass: chinical significance and implications for practice. Am J Crit Care 2004;13:384–93.
Andrejaitiene J, Sirvinskas E, Bolys R. The influence of cardiopulmonary bypass on respiratory dysfunction in early postoperative period. Medicina 2004;40 (Suppl. 1):7–12.
Westerdahl E, Lindmark B, Almgren S, Tenling A. Chest physiotherapy after coronary artery bypass graft surgery: a comparison of three different deep breathing techniques. J Rehabil Med 2001;33:79–84.
Shenkman Z, Shir Y, Weiss YG, Bleiberg B, Gross D. The effects of cardiac surgery on early and late pulmonary functions. Acta Anaesthesiol Scand 1997;41:1193–9.
Kirklin JK, Westaby S, Blackstone EH, Kirklin JW, Chenoweth DE, Pacifico AD. Complement and the damaging effects of cardiopulmonary bypass. J Thorac Cardiovasc Surg 1983;86:845–57.
Royston D, Minty BD, Higenbottam TW, Wallwork J, Jones GJ. The effect of surgery with cardiopulmonary bypass on alveolar-capillary barrier function in human beings. Ann Thorac Surg 1985;40:139–43.
Serdar Çimena, Vedat Özkulb, Bülent Ketencia, Nurgül Yurtsevenb, Rafet Günaya, et al. Daily comparison of respiratory functions between on-pump and off-pump patients undergoing CABG. Eur J Cardiothorac Surg 2003;23:589–94.
Berrizbeitia LD, Tessler S, Jacobowitz IJ, Kaplan P, Budzilowicz L, Cunningham JM. Effect of sternotomy and coronary bypass surgery on postoperative pulmonary mechanics: comparison of internal mammary and saphenous vein bypass grafts. Chest 1989;96:873–6.
Cohen AJ, Moore P, Jones C, Miner TJ, Carter WR, Zurcher RP, et al. Effect of internal mammary harvest on postoperative pain and pulmonary function. Ann ThoracSurg 1993;56:1107–9.
Mathers J, Benumof JL, Wahrenbrock EA. General anesthetics and regional hypoxic pulmonary vasoconstriction. Anesthesiology 1077;46:11–14.
Egbert LD, Laver MB, Bendixen HH. Intermittent deep breaths and compliance during anesthesiain man. Anesthesiology 1963;24:57–60.
Jenkins SC, Soutar SA, Loukota JM, Johnson LC, Moxham J. Physiotherapy after coronary artery surgery: are breathing exercises necessary? Thorax 1989;44:634–9.
Jindani A, Aps C, Neville E, Sonmez B, Tun K, Williams BT, et al. Postoperative cardiac surgical care: an alternative approach. Br Heart J 1993;69:59–63.
Singh NP, Vargas FS, Cukier A, Terra-Filho M, Teixeira LR, Light RW. Arterial blood gases after coronary artery bypass surgery. Chest 1992;102:1337–41.
