Citation Information :
Kumar A, Verma SK, Mehrotra A, Kumar A, Chaudhri S, Verma C. A Study on Microalbuminuria in Patients with Chronic Obstructive Pulmonary Disease at a Tertiary Care Centre in North India. Indian J Chest Dis Allied Sci 2017; 59 (1):17-21.
Background. In chronic obstructive pulmonary disease (COPD), systemic effects of the disease result in structural and/or biochemical alterations in structures or organs other than the lungs. Microalbuminuria (MAB) is an importantC risk factor for cardiovascular disease, and it may be seen due to hypoxaemia in patients with COPD.
Objective. Present study was undertaken to find the presence of MAB in COPD and relationship of MAB with clinical and physiological parameters in stable patients with COPD.
Methods. Sixty patients with COPD and 50 healthy controls were enrolled in the study. Spot urinary albumin/creatinine ratio, smoking history, spirometry, blood gases, body mass index, kidney function tests and BODE index (body-mass index, airflow obstruction, dyspnoea and exercise) were assessed. Frequency of MAB was compared between cases and controls.
Results. Of 60 cases, 50 (83%) were males and 10 (17%) were females. In patients with COPD, MAB was found in all of them (100%) while in controls only 4 (10%) had MAB (p<0.0001).
Conclusion. In the present study, MAB was seen in all the patients with COPD and MAB levels were significantly high in COPD cases compared with asymptomatic smokers with normal spirometry.
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