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VOLUME 61 , ISSUE 3 ( July-September, 2019 ) > List of Articles

CASE REPORT

Coexistent ABPA and Tuberculosis Presenting as Lung Collapse with Respiratory Failure

Saurabh Mittal, Mohammad Amir, Nattusamy Loganathan, Anant Mohan, Karan Madan

Keywords : Allergic bronchopulmonary aspergillosis, Tuberculosis, Lung collapse

Citation Information : Mittal S, Amir M, Loganathan N, Mohan A, Madan K. Coexistent ABPA and Tuberculosis Presenting as Lung Collapse with Respiratory Failure. Indian J Chest Dis Allied Sci 2019; 61 (3):147-149.

DOI: 10.5005/ijcdas-61-3-147

License: CC BY-NC 4.0

Published Online: 18-11-2022

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

A 30-year-old female presented with respiratory failure and left lung collapse. Possibility of tumour related endobronchial obstruction was considered. Bronchoscopy revealed thick mucus in the left main bronchus, acid-fast bacilli were present on examination of bronchial washings and Gene-Xpert test was positive for Mycobacterium tuberculosis. In view of significant mucoid impaction, possibility of allergic bronchopulmonary aspergillosis was considered. Serum Aspergillus specific immunoglobulin E levels, Aspergillus precipitins and total serum immunoglobulin E levels were elevated. A diagnosis of allergic bronchopulmonary aspergillosis co-existent with pulmonary tuberculosis was made. Patient was treated with anti-tuberculosis therapy along with oral corticosteroids.


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  1. Agarwal R. Allergic bronchopulmonary aspergillosis. Chest 2009;135:805–26.
  2. Agarwal R, Aggarwal AN, Gupta N, Gupta D. A rare cause of acute respiratory failure--allergic bronchopulmonary aspergillosis. Mycoses 2011;54:e223–7.
  3. Agarwal R, Singh N, Aggarwal AN. An unusual association between Mycobacterium tuberculosis and Aspergillus fumigatus. Monaldi Arch Chest Dis 2016. Available from URL: http://monaldiarchives. org/index.php/macd/article/view/409.
  4. Gupta M, Roshan R, Chhabra SK. Allergic bronchopulmonary aspergillosis without asthma complicating pulmonary tuberculosis. Lung India 2012;29:286–8.
  5. Min KH, Park SJ, Kim SR, Lee MH, Chung CR, Han HJ, et al. Coexistence of allergic bronchopulmonary aspergillosis and active pulmonary tuberculosis. Am J Respir Crit Care Med 2011;183:137–9.
  6. Madan K, Aggarwal AN, Bhagat H, Singh N. Acute respiratory failure following traumatic tooth aspiration. BMJ Case Rep 2013. Available from URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603903/
  7. Greenberger PA. Allergic bronchopulmonary aspergillosis. In: Middleton E Jr, Reed CE, Ellis EF, Franklin AN Jr, Yunginger JW, Busse WW, editors Allergy: Principles and Practice; 5th edition. St. Louis (MO): Mosby; 1998: pp 981–93.
  8. Agarwal R, Aggarwal AN, Gupta D, Jindal SK. Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with bronchial asthma: systematic review and metaanalysis. Int J Tuberc Lung Dis 2009;13:936–44.
  9. Agarwal R, Sehgal IS, Dhooria S, Aggarwal AN. Developments in the diagnosis and treatment of allergic bronchopulmonary aspergillosis. Expert Rev Respir Med 2016;10:1317–34.
  10. Garg MK, Sharma M, Agarwal R, Aggarwal AN, Gupta P, Sodhi KS, et al. Allergic bronchopulmonary aspergillosis: all a radiologist needs to know [Internet]. Curr Pediatr Rev 2016. Available from URL: http://www.eurekaselect.com/145196/article
  11. Muthu V, Behera D, Agarwal R. Allergic bronchopulmonary aspergillosis or pulmonary tuberculosis: a case of mistaken identity? Lung India 2015;32:529–30.
  12. Madan K, Bal A, Agarwal R. Pleural effusion in a patient with allergic bronchopulmonary aspergillosis. Respir Care 2012;57:1509–13.
  13. Moss RB. Pathophysiology and immunology of allergic bronchopulmonary aspergillosis. Med Mycol 2005;43 (Suppl. 1): S203–206.
  14. Tan YJ, Zhang YB, Feng DY, Xie B, Lin ZY, Chen HG, et al. The change and the clinical significance of peripheral blood Th1/Th2 cells in patients with pulmonary tuberculosis. Zhonghua JieHe He Hu Xi Za Zhi 2004;27:385–9.
  15. Bhurayanontachai R, Maneenil K. Factors influencing development and mortality of acute respiratory failure in hospitalized patient with active pulmonary tuberculosis: a 10- year retrospective review. J Thorac Dis 2016;8:1721–30.
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