VOLUME 62 , ISSUE 1 ( January-March, 2020 ) > List of Articles
Satyajeet Sahoo, Sourin Bhuniya, Mukund N Sable
Keywords : Renal cell carcinoma, Endobronchial metastasis, Total lung collapse, Polypoidal mass
Citation Information : Sahoo S, Bhuniya S, Sable MN. Endobronchial Metastasis from Resected Renal Cell Carcinoma: An Unusual Presentation After Four Years. Indian J Chest Dis Allied Sci 2020; 62 (1):23-25.
DOI: 10.5005/ijcdas-62-1-23
License: CC BY-NC 4.0
Published Online: 07-11-2022
Copyright Statement: Copyright © 2020; The Author(s).
Endobronchial metastasis (EBM) from renal cell carcinoma (RCC) mimicking endobronchial obstruction due to bronchogenic carcinoma is rare. Total lung collapse due to EBM from RCC is even more uncommon. We report the case of a female patient who presented with cough, dyspnoea and collapse of the right lung. She gave a history of nephrectomy on the left side four years back for some malignant lesion. On bronchoscopy, a polypoidal mass was observed which completely occluded the right main bronchus with features of clear cell adenocarcinoma. Immunohistochemistry was positive for CD 10 as well as PAX-8 and negative for thyroid transcription factor-1 (TTF-1) and Napsin, suggestive of metastatic renal cell carcinoma. The patient had multiple metastases in the brain and the adrenal gland also. She was started on pazopanib and given intracranial radiation but died after two months. Our case highlights the importance of making a distinction between EBM from the primary lung cancers because the treatment modalities differ significantly.