Background: India is still a high tuberculosis (TB) burden country in the world and risk factors of the disease are also highly prevalent. Survival analysis of TB patients had not been adequately studied, especially in this part of the country. The present study was undertaken to estimate overall survival time of TB patients and to find out association of different co-variates with outcome event (death) and survival time of TB patients. Methods: A record-based retrospective cohort study was conducted in a Tuberculosis Unit of Purba Bardhaman District, West Bengal, India. All registered TB cases in the unit, excluding resistant cases, between October 2010 to March 2016 were included as study subjects (N=3110) and followed up till June 2017 for outcome of interest. Actual data collection and analysis from relevant registers of the Tuberculosis Unit were carried out during June 2017 to November 2017. Descriptive statistics, Kaplan-Meier survival analysis, Log rank test and Cox proportional hazard model for multivariate analysis were applied. Results: Of 3110 patients, 6.9% (214) had the outcome event of interest (death). The overall mean survival time was 518 days (95% confidence interval 480.9-555.3). Male gender, category II TB, pulmonary TB and TB with human immunodeficiency virus (HIV) were found to be significant risk factors for death due to TB. Conclusions: Overall survival time was significantly low among males, re-treatment cases, patients with pulmonary TB and patients with HIV co-infection. Awareness generation, adherence to treatment, early diagnosis and treatment are some necessary measures to be properly implemented.