Objective: Bronchiectasis is a suppurative lung disease characterised by wide and distorted bronchi, with profuse expectoration, resulting in impaired qualityof- life. The present study evaluated the clinico-radiological and functional characteristics of patients with bronchiectasis. Methods: A hospital-based, prospective, cross-sectional study was conducted for one year. Chest radiograph followed by high resolution computed tomography was done in patients with features suggestive of bronchiectasis. All patients were assessed with spirometry, sputum gram-stain and pyogenic culture-sensitivity. Severity was assessed using FACED score. Results: Eighty patients (38 males) were included in the study with a mean age of 47.0±13.7 years. Average lung involvement was ≥2 lobes and cystic bronchiectasis was the most common abnormality. Shortness of breath (91%) and cough with expectoration (87%) were the most frequent complaints. The most common functional impairment was obstructive (58.7%), with a mean percent predicted forced expiratory volume in first second (FEV1) of 55.8±15.1. The patients with Pseudomonas spp growth in sputum culture had more severe disease in the form of more number of lobes involvement and cystic destruction (P<0.001). Conclusions: Bronchiectasis is a progressive disease with significant morbidity and mortality. While radiology plays an important role in the diagnosis, microbiology is an important aspect in the management of the diseases as well as in preventing exacerbations/disease progression.