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VOLUME 63 , ISSUE 2 ( April-June, 2021 ) > List of Articles

Original Article

Association Between Asthma and Obstructive Sleep Apnoea

Anshu Priya, Nitin Goel, Kamal Singh, Raj Kumar

Keywords : Asthma, Obstructive sleep apnoea, Polysomnography, Asthma control, Quality-of-life

Citation Information : Priya A, Goel N, Singh K, Kumar R. Association Between Asthma and Obstructive Sleep Apnoea. Indian J Chest Dis Allied Sci 2021; 63 (2):95-99.

DOI: 10.5005/ijcdas-63-2-95

License: CC BY-NC 4.0

Published Online: 18-11-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Background: Asthma and obstructive sleep apnoea (OSA) are the commonest pulmonary diseases worldwide and contribute to significant morbidity and mortality. Methods: Fifty patients aged 18 years and above with moderate to severe asthma, presented to our out-patient clinic during 2016-2017, were screened for OSA using a self-reported STOP BANG Questionnaire. Of these, 30 were found to be at risk of OSA (STOP BANG score > 2) and were included in the study. These 30 patients underwent diagnostic polysomnography (PSG), inflammatory markers interleukin (IL)-4, IL-5, IL-6, IL-13, high sensitivity c-reactive protein, fractional exhaled nitric oxide (FeNO) testing. Their quality-of-life and asthma control was evaluated with St. George Respiratory Questionnaire score and Asthma Control Test, respectively. Results: After PSG, OSA, apnoea-hypopnoea index (AHI) > 5/h was found in 15/30 (50%) cases with moderate and severe asthma (N=15 each). In moderate asthma 6/15 (40%) and in severe asthma 9/15(60%) were diagnosed to have OSA. Asthma patients with OSA fared poorly in asthma control test questionnaire and St. George's Respiratory Questionnaire (P=0.01) in comparison to those without OSA. Conclusions: Our study indicates high prevalence of OSA among patients of moderate to severe asthma which negatively affects quality of sleep and asthma control that further leads to poor quality-of-life in these patients. Thus, highlighting the need of maintaining high index of suspicion in identifying OSA among patients of moderate to severe asthma.

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