Citation Information :
Gowrinath K, Manu MK, Chawla K. Nocardia otitidiscaviarum as Possible Etiologic Agent of Non-resolving Pneumonia. Indian J Chest Dis Allied Sci 2022; 64 (2):108-110.
Nocardia otitidiscaviarum is an infrequent cause of nocardial pneumonia and rarely affects non-immunocompromised individuals. Pneumonia may not resolve if the causative organism is not susceptible to the empirically given antimicrobial drug. Amoxicillin–clavulanic acid is a commonly used initial empiric antibiotic for suspected community-acquired bacterial pneumonia on outpatient basis. We report an unusual case of N. otitidiscaviarum as a possible etiologic agent of non-resolving pneumonia due to amoxicillin-clavulanic acid resistance in a previously healthy adult male.
Brown-Elliot BA, Brown JM, Conville PS, et al. Clinical and laboratory features of the Nocardia spp. based on current molecular taxonomy. Clin Microbiol Rev 2006;19(2):259–282. DOI: 10.1128/CMR.19.2.259-282.2006.
Huang L, Chen X, Xu H, et al. Clinical features, identification, antimicrobial resistance patterns of Nocardia species in China 2009-2017. Diagn Microbiol Infect Dis 2019;94(2):165–172. DOI: 10.1016/j.diagmicrobio.2018.12.007.
McNeill MM, Brown JM. Medically important aerobic actinomycetes: epidemiology and microbiology. Clin Microbiol Rev 1994;7(3):357–417. DOI: 10.1128/cmr.7.3.357.
National Committee for Clinical Laboratory Standards. Susceptibility testing of nocardia, mycobacteria and other actinomycetes: approved standards. National Committee for Clinical Laboratory Standards Document N24-A, 2003. Wayne, PA: National Committee for Clinical Laboratory Standards.
Zheng S-W. Disseminated nocardiosis due to Nocardia otitidiscaviarum: a case report and literature review. Asia Pacific J Trop Med 2019;12(4):185–194. DOI: 10.4103/1995-7645.257120.
Singh A, Chhina D, Soni RK, et al. Clinical spectrum and outcome of pulmonary nocardiosis: 5-year experience. Lung India 2016;33(4):398–403. DOI: 10.4103/0970-2113.184873.
Taneja J, Sen B, Dang N. Pulmonary nocardiosis mimicking malignancy. Indian J Med Microbiol 2016;34(1):117–118. DOI: 10.4103/0255-0857.167680.
Chawla K, Mukhopadhyay C, Payyanur P, et al. Pulmonary nocardiosis from a tertiary care hospital in Southern India. Trop Doc 2009;39(3):163–165. DOI: 10.1258/td.2008.080229.
Rudramurthy SM, Honnavar P, Kaur H, et al. Molecular identification of clinical Nocardia isolates from India. J Med Microbiol 2015;64(10):1216–1225. DOI: 10.1099/jmm.0.000143.
Marin M, Ruiz A, Iglesian C, et al. Identification of Nocardia species from clinical isolates using MALDI-TOF mass spectrometry. Clin Microbiol Infect 2018;24(12):1342.e5–1342.e8. DOI: 10.1016/j.cmi.2018.06.014.
Valdezate S, Garrido N, Carrasco G, et al. Epidemiology and susceptibility to antimicrobial agents of the main Nocardia species in Spain. J Antimicrob Chemother 2017;72(3):754–761. DOI: 10.1093/jac/dkw489.
