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VOLUME 52 , ISSUE 2 ( April-June, 2010 ) > List of Articles

Original Article

Validation of a Hindi Translation of Mini Asthma Quality of Life Questionnaire in North Indian Patients with Bronchial Asthma

Ashutosh N. Aggarwal, Dheeraj Gupta

Keywords : Bronchial asthma, Cross-cultural adaptation, Quality of life, Questionnaires, Reliability, Validity

Citation Information : Aggarwal AN, Gupta D. Validation of a Hindi Translation of Mini Asthma Quality of Life Questionnaire in North Indian Patients with Bronchial Asthma. Indian J Chest Dis Allied Sci 2010; 52 (2):83-89.

DOI: 10.5005/ijcdas-52-2-83

License: CC BY-NC 4.0

Published Online: 10-06-2022

Copyright Statement:  Copyright © 2010; The Author(s).


Background and Objective. There is little information on validated health-related quality of life (HRQoL) instruments for use in Indian patients with bronchial asthma. We attempted to validate the Hindi translation of Juniper's mini asthma quality of life questionnaire (MiniAQLQ) in north Indian patients with bronchial asthma. Methods. Hindi translation of MiniAQLQ, and abbreviated World Health Organization quality of life questionnaire (WHOQOL-Bref), were administered to 30 patients with bronchial asthma twice at a six-week interval. Clinical and physiological data were also recorded. Psychometric properties (acceptability, validity, reliability and responsiveness) of MiniAQLQ were assessed after calculating four domain (physical, psychological, social relationships and environment), and a total score. Results. Most questionnaires were returned without missing responses. MiniAQLQ had good convergent and discriminant validity, but moderate content and construct validity. All components (except emotional function domain) met standards for internal consistency (Cronbach's alpha coefficient > 0.70), but intra-class correlation coefficients were variable. Change in MiniAQLQ scores between two assessments correlated poorly with corresponding changes in lung function. The effect sizes ranged from 0.02 to 0.34 in 11 patients whose forced expiratory volume in the first second (FEV1) changed by > 200mL and > 12% from baseline, and were considered small. Conclusion. The Hindi translation of MiniAQLQ is a moderately good discriminative and a relatively poor evaluative instrument to assess health related quality of life (HRQoL) in north Indian patients with bronchial asthma.

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  1. Aggarwal AN, Chaudhry K, Chhabra SK, D'Souza GA, Gupta D, Jindal SK, et al. Prevalence and risk factors for bronchial asthma in Indian adults: a multicentre study. Indian J Chest Dis Allied Sci 2006;48:13-22.
  2. Rutten-van Molken MP, Custers F, van Doorslaer EK, Jansen CC, Heurman L, Maesen FP, et al. Comparison of performance of four instruments in evaluating the effects of salmeterol on asthma quality of life. Eur Respir J 1995;8:888-98.
  3. Juniper EF, Norman GR, Cox FM, Roberts JN. Comparison of the standard gamble, rating scale, AQLQ and SF-36 for measuring quality of life in asthma. Eur Respir J 2001;18:38-44.
  4. Juniper EF, Guyatt GH, Cox FM, Ferrie PJ, King DR. Development and validation of the Mini Asthma Quality of Life Questionnaire. Eur Respir J 1999;14:32-8.
  5. Juniper EF, Buist AS, Cox FM, Ferrie PJ, King DR. Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest 1999;115:1265-70.
  6. (Accessed on March 25, 2009)
  7. Chhabra SK, Kaushik S. Validation of the asthma quality of life questionnaire (AQLQ-UK English version) in Indian asthmatic subjects. Indian J Chest Dis Allied Sci 2005;47:167-73.
  8. Moudgil H, Marshall T, Honeybourne D. Asthma education and quality of life in the community: a randomised controlled study to evaluate the impact on white European and Indian subcontinent ethnic groups from socioeconomically deprived areas in Birmingham, UK. Thorax 2000;55:177-83.
  9. Jindal SK, Wahi PL. Pulmonary function laboratory in the tropics: needs, problems and solutions. In: Sharma OP, editor. Lung Disease in the Tropics. New York: Marcel Dekker; 1991: pp 523-42.
  10. Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. 2007. Available from URL: (Accessed on March 25, 2009).
  11. Saxena S, Chandramani K, Bhargava R. WHOQOL-Hindi: a questionnaire for assessing quality of life in health care settings in India. World Health Organization Quality of Life. Natl Med J India 1998;11:160-5.
  12. Fletcher A, Gore S, Jones D, Fitzpatrick R, Spiegelhalter D, Cox D. Quality of life measures in health care. II. Design, analysis, and interpretation. Br Med J 1992;305:1145-8.
  13. Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika 1951;16:297-334.
  14. Kazis LE, Anderson JJ, Meenan RF. Effect sizes for interpreting changes in health status. Med Care 1989;27(3 Suppl):S178-89.
  15. Cohen J. Statistical Power Analysis for the Behavioral Sciences. Second edn. Hillsdale, NJ: Lawrence Earlbaum Associates; 1988.
  16. National Centre for Health Outcomes Development. A structured review of patient-reported measures in relation to selected chronic conditions, perceptions of quality of care and carer impact. Oxford, UK: Department of Public Health, University of Oxford; 2006.
  17. Aggarwal AN, Gupta D, Kumar T, Singh N, Jindal SK. Validation of Hindi translation of St. George's Respiratory Questionnaire in Indian patients with chronic obstructive pulmonary disease. Indian J Chest Dis Allied Sci 2007;49:87-91.
  18. Baghi H, Atherton M. Construct validity and reliability of scores on scales to measure the impairment of health-related quality of life in persons with asthma. J Nurs Meas 2004;12: 21-31.
  19. Magid DJ, Houry D, Ellis J, Lyons E, Rumsfeld JS. Health-related quality of life predicts emergency department utilization for patients with asthma. Ann Emerg Med 2004;43: 551-7.
  20. van der Molen T, Postma DS, Schreurs AJ, Bosveld HE, Sears MR, Meyboom de Jong B. Discriminative aspects of two generic and two asthma-specific instruments: relation with symptoms, bronchodilator use and lung function in patients with mild asthma. Qual Life Res 1997;6:353-61.
  21. Carranza-Rosenzweig JR, Edwards L, Lincourt W, Dorinsky P, ZuWallack RL. The relationship between health-related quality of life, lung function and daily symptoms in patients with persistent asthma. Respir Med 2004;98:1157-65.
  22. Almada-Lobo F, Almada-Lobo B. Quality of life in asthmatic outpatients. J Asthma 2008;45:27-32.
  23. Anderson RT, Aaronson NK, Wilkin D. Critical review of the international assessments of health-related quality of life. Qual Life Res 1993;2:369-95.
  24. Kirshner B, Guyatt G. A methodological framework for assessing health indices. J Chronic Dis 1985;38:27-36.
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