The Indian Journal of Chest Diseases and Allied Sciences

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VOLUME 53 , ISSUE 1 ( January-March, 2011 ) > List of Articles

Original Article

Prevalence of Depression in Stable Chronic Obstructive Pulmonary Disease

Sajal De

Keywords : Depression, PHQ-9, Chronic obstructive pulmonary disease

Citation Information : De S. Prevalence of Depression in Stable Chronic Obstructive Pulmonary Disease. Indian J Chest Dis Allied Sci 2011; 53 (1):35-40.

DOI: 10.5005/ijcdas-53-1-35

License: CC BY-NC 4.0

Published Online: 10-06-2022

Copyright Statement:  Copyright © 2011; The Author(s).


Abstract

Background. Psychological impairment is a significant co-morbid condition of chronic obstructive pulmonary disease (COPD). No studies from India have been conducted to assess the prevalence of depression in COPD. Methods. We investigated the prevalence of depression in 100 consecutive stable COPD patients during their routine outpatient department visits. Patients diagnosed to have depression or chronic systemic diseases were excluded. Severity of the COPD was classified according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Hindi translations of patient health questionnaire-9 (PHQ-9) were administered and severity of depression was assessed at each stage of the COPD. Results. All subjects were males with a mean age of 61.7±9.6 years. Six patients in stage I, 32 patients in stage II, 40 patients in stage III and 22 patients in stage IV of the COPD were enrolled. The cumulative prevalence of depression in the study population was 72 percent. Conclusions. Symptoms of depression were observed at all stages of COPD and its severity increased with an increase in severity of the COPD. High prevalence of depressive symptoms in Indian patients with COPD may be due to various confounding factors. Screening for symptoms of depression in patients with COPD by simple and quick validated questionnaires during their out-patient visits will be helpful in early diagnosis and appropriate treatment or referral.


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  1. Yohannes AM, Baldwin RC, Connolly MJ. Prevalence of sub-threshold depression in elderly patients with chronic obstructive pulmonary disease. J Geriatric Psychiatry 2003;18:412-6.
  2. Bemt LVD, Schermer T, Bor H, Smink R, Baumgarten EW, Lucassen P, et al. The risk for depression co morbidity in patients with COPD. Chest 2009;135:108-14.
  3. Hill K, Geist R, Goldstein RS, Lacasse Y. Anxiety and depression in end-stage COPD. Eur Respir J 2008;31:667-77.
  4. Maurer J, Rebbapragada V, Borson S, Goldstein R, Kunik ME, Yohannes AM, et al for the ACCP Workshop Panel on Anxiety and Depression in COPD. Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest 2008;134:43-56.
  5. Gudmundsson G, Gislason T, Janson C, Lindberg E, Ulrik CS, Brondum E, et al. Depression, anxiety and health status after hospitalisation for COPD: a multicentre study in the Nordic countries. Respir Med 2006;100:87-93.
  6. Spitzer RL, Kroenke K, Williams JBW and the Patient Health Questionnaire Primary Care Study Group. Validation and utility of a self-report version of PRIMEMD: the PHQ primary care study. JAMA 1999;282:1737- 44.
  7. Kochhar PH, Rajadhyaska SS, Suvarna VR for PRIMEMD Study Group. Translation and validation of brief patient health questionnaire against DSM IV as a tool to diagnose major depressive disorder in Indian patients. J Psotgrad Med 2007;53:102-7.
  8. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al. Standardization of spirometry. Eur Respir J 2005;26:319-38.
  9. Global Strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. Updated 2008. Available at URL: http:\\www.goldcopd. com (Accessed on April 4, 2009).
  10. Solano JP, Gomes B, Higginson IJ. A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manage 2006;31:58-69.
  11. Mulrow CD, Williams JW, Gerety MB, Ramirez G, Montiel OM, Kerber C. Case-finding instruments for depression in primary care settings. Ann Intern Med 1995;122:913-21.
  12. Kunik ME, Roundy K, Veazey C, Souchek J, Richardson P, Wray NP, et al. Surprisingly high prevalence of anxiety and depression in chronic breathing disorders. Chest 2005; 127:1205-11.
  13. Poongothai S, Pradeepa R, Ganesan A, Mohan V. Prevalence of depression in a large urban south Indian population: the Chennai Urban Rural Epidemiology Study (Cures-70). PLoS ONE 4(9): e7185. doi:10.1371/journal.pone.0007185.
  14. Singh G, Sachdev JS, Kaur H. Prevalence of depression among medical in-patients. Indian J Psychiatry 1979;21: 274-8.
  15. Avasthi A, Varma SC, Kulhare P, Nehra R, Grover S, Sharma S. Diagnosis of common mental disorders by using PRIME-MD patient health questionnaire. Indian J Med Res 2008;127:159-64.
  16. Wagena EJ, Arrindell WA, Wouters EFM, Schayck CPV. Are patients with COPD psychologically distressed? Eur Respir J 2005;26:242-8.
  17. Manen JGV, Bindels PJE, Dekker FW, Jzermans CJI, Zee JSV, Schade E. Risk of depression in patients with chronic obstructive pulmonary disease and its determinants. Thorax 2002;57:412-6.
  18. Guell R, Resqueti V, Sangenis M, Morante F, Martorell B, Casan P, et al. Impact of pulmonary rehabilitation on psychosocial morbidity in patients with severe COPD. Chest 2006;129:899-904.
  19. Khaled SM, Bulloch A, Exner DV, Patten SB. Cigarette smoking, stages of change, and major depression in the Canadian population. Can J Psychiatry 2009;54:204-8.
  20. Breslau N, Kilbey MM, Andreski P. Nicotine dependence, major depression and anxiety in young adults. Arch Gen Psychiatry 1991;48:1609-74.
  21. Salvi SS, Barnes PJ. Chronic obstructive pulmonary disease in non-smokers. Lancet 2009;374:733-43.
  22. Marco FD, Verga M, Reggente M, Morante F, Martorell B, Casan P, et al. Anxiety and depression in COPD: how much do they contribute to physical symptoms and functional status? Respir Med 2006;100:1767-74.
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