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VOLUME 65 , ISSUE 3 ( July-September, 2023 ) > List of Articles


Pulmonary Sarcomatoid Carcinoma Presenting as Massive Pleural Effusion

Sonam Spalgais, Parul Mrigpuri, AS Dhilnaz, Tsewang Chorol, Raj Kumar

Keywords : Biopsy, Case report, Effusion, Pulmonary, Sarcomatoid, Tumor

Citation Information : Spalgais S, Mrigpuri P, Dhilnaz A, Chorol T, Kumar R. Pulmonary Sarcomatoid Carcinoma Presenting as Massive Pleural Effusion. Indian J Chest Dis Allied Sci 2023; 65 (3):142-146.

DOI: 10.5005/jp-journals-11007-0083

License: CC BY-NC 4.0

Published Online: 05-02-2024

Copyright Statement:  Copyright © 2023; The Author(s).


Pulmonary sarcomatoid carcinoma (PSC) is an extremely rare subtype of non-small cell lung carcinoma (NSCLC) commonly seen in elderly smoker males with non-specific clinical features. The confirmed diagnosis is done if tumor contains both sarcomatoid and epithelial components with at least 10% of the tumor and usually requires IHC confirmation. The preoperative diagnosis is very difficult due to the rarity of the disease and histological over/under presentation. Pleural involvement with effusion is not a common presenting feature of PSC. The tumor is usually locally advanced with a poor prognosis and had poor survival rate. We report a unique and rare case of PSC in a middle-aged, non-smoker lady with massive pleural effusion. She presented with sudden onset massive effusion. The computed tomography (CT) chest showed massive effusion with multiple pleural nodules and thickening. The diagnosis was confirmed by histopathology and immune histochemical (IHC) staining of thoracoscopic pleural biopsy.

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