COVID-19 infection during pregnancy presents unique challenges, particularly in managing respiratory distress. Oxygen therapy emerges as a pivotal intervention, warranting meticulous attention and tailored strategies. This review explores the significance of oxygen therapy in mitigating hypoxemia, examining its implications, potential complications, and the imperative for meticulously structured protocols. With an emphasis on optimizing maternal–fetal outcomes, this comprehensive analysis underscores the need for evidence-based approaches, close monitoring, and individualized protocols for pregnant women combating COVID-19-associated respiratory compromise. This abstract encapsulates the focus on oxygen therapy's significance, the complexities surrounding its use, and the necessity for precisely defined protocols in managing COVID-19 in pregnant individuals, utilizing scientific language and keywords to appeal to a specialized readership.
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