The Indian Journal of Chest Diseases and Allied Sciences

Register      Login

VOLUME 66 , ISSUE 2 ( April-June, 2024 ) > List of Articles

CASE REPORT

Primary Multidrug-resistant Tuberculosis of the Breast: A Rare Entity

Aditya Aggarwal, Jaanakhi Velayutham Muthu, Shubhra Jain, Vinod Joshi

Keywords : Bedaquiline, Cartridge-based nucleic acid amplification test, Case report, Line probe assay, Second-line injectables

Citation Information : Aggarwal A, Muthu JV, Jain S, Joshi V. Primary Multidrug-resistant Tuberculosis of the Breast: A Rare Entity. Indian J Chest Dis Allied Sci 2024; 66 (2):57-59.

DOI: 10.5005/jp-journals-11007-0110

License: CC BY-NC 4.0

Published Online: 10-07-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

A 41-year-old female patient presented with a painful swelling in right breast for 6 months. Pus was aspirated and subjected to cartridge-based nucleic acid amplification test (CBNAAT) and line probe assay (LPA) which confirmed it as a case of multidrug-resistant tuberculosis. Isolates were resistant to rifampicin (R) and second-line injectables (SLI). The patient improved on bedaquiline (BDQ)-containing regimen.


HTML PDF Share
  1. WHO Global Tuberculosis Report 2023. Available from: https://www.who.int/tb/publications/global_report/en/.
  2. Cooper A. Illustration of the diseases of the breast. In: Longmans, Orme, Brown, Green, editors. Part I. London: 1829. p. 7.
  3. Tewari M, Shukla HS. Breast tuberculosis: Diagnosis, clinical features and management. Indian J Med Res 2005;122:103–110. PMID: 16177466.
  4. Marinopoulos S, Lourantou D, Gatzionis T, et al. Breast tuberculosis: Diagnosis, management and treatment. Int J Surg Investig Case Reports 2012;31:548–550. DOI: 10.1016/j.ijscr.2012.07.003.
  5. Kumar P, Sharma N. Primary MDR-TB of the breast. Indian J Chest Dis Allied Sci 2003;45:63–65. PMID: 12683714.
  6. Giri VP. Primary multidrug-resistant tuberculosis of the breast – A rare presentation. Ann Med Health Sci Res 2017;7:70–72.
  7. Gupta V, Mohan H, Jain P, et al. Tuberculous mastitis: A report of two cases in elderly females. Jpn J Infect Dis 2006;59:279–280. PMID: 16936356.
  8. Gupta A, Bains L, Yadav D, et al. Tubercular mastitis: An institutional experience from a tertiary care centre of Northern India. Asian J Med Sci 2017;8:72–75. DOI: 10.3126/ajms.v8i3.16847.
  9. Kant s, Dua E, Goel MM. Bilateral tubercular mastitis. Lung India 2007;24:90–93. DOI: https://doi.org/10.4103/0970-2113.44222.
  10. Mckeown KC, Wilkinson KW. Tuberculous diseases of the breast. Br J Surg 1952;39:420. DOI: 10.1002/bjs.18003915705.
  11. Sen M, Gorpeligoglu C, Bozer M. Isolated primary breast tuberculosis-Report of three cases and review of literature. Clinics (Sao Paulo) 2009; 64:607–610. DOI: 10.1590/s1807-59322009000600019.
  12. Hiremath BV, Subramaniam N. Primary breast tuberculosis: Diagnostic and therapeutic dilemmas. Breast Dis 2015;35:187–193. DOI: 10.3233/BD-150407.
  13. Prathima S, Kalyani R, Parimala S. Primary tubercular mastitis masquerading as malignancy. J Nat Sci Bio Med 2014;5:184–186. DOI: 10.4103/0976-9668.127324.
  14. Gambhir S, Ravina M, Rangan K, et al. Imaging in extrapulmonary tuberculosis. Int J Infect Dis 2017;56:237–247. DOI: 10.1016/j.ijid.2016.11.003.
  15. Guidelines for Programmatic Management of Drug Resistant Tuberculosis in India-2021: Ministry of Health and Family Welfare. Tbcindia.gov.in. 2021 [cited 17 June 2022]. Available from: https://tbcindia.gov.in/showfile.php?lid=3590.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.